Lions Mane Supplements

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Someone has recommended Lions Mne supplement, has anyone else had these and been on Clopidogrel? Thanks

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  • How Clopidogrel Works : Clopidogrel is an antiplatelet medication. It works by preventing platelets in your blood from sticking together and forming clots, which is crucial for preventing heart attacks and strokes .
  • Lion’s Mane’s Effect : In vitro (laboratory) research has shown that extracts from Lion’s Mane mushroom can also inhibit platelet aggregation . This means it has a similar effect to your medication.
  • The Combined Effect : The concern is that taking Lion’s Mane alongside Clopidogrel could have an additive or synergistic effect . This means your blood’s ability to clot could be reduced more than intended, potentially leading to easier bruising or a higher risk of bleeding, which in rare cases could be serious .
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I had Lion’s Mane supplements a few years back. Finished the bottle and didn’t return to it for no other reason than I forgot to continue. Many ingestible comestibles interact with Clopidogrel, many have anti-coagulant properties. Wine for instance is a mild anti-coagulant and I was drinking that when I had an ischaemic stroke.

Bleeding doesn’t necessarily mean bleeding in the brain, it could be in the stomach or anywhere else in the body. It depends on how risk averse one is and the quantity and concentration of what you wish to try that ultimately determines possible contraindications.

As for Lion’s Mane itself, I don’t think there is a lot of evidence of neurogenesis, there may be some evidence of cognitive performance but one can get that from caffeine too. However, even that may be circumstantial. It’s a very on-trend supplement at the moment promoted by health influencers with financial agendas.

Having said all that, Lion’s Mane is considered a delicious, gourmet mushroom with a lobster like taste, you could introduce it into your diet just for the taste value if not the cognitive benefit, yet, to me those go hand in hand anyway, good food equals good mood. Though, don’t forage for it in the UK because it is illegal, probably stemming from its rarity due to health influencers encouraging people to go pick it. :thinking:

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@Nanag I do not take any supplements as I had gone and bought three different ones to improve my use of my legs, however after buying I was then told you cannot take with blood thinners. I was so disappointment a I had no idea something you see as good is bad for you because of the medication you take. Someone else on here will have more to share with you, Good luck :four_leaf_clover: Check with you GP as they will guide you.

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What were they, out of curiosity?

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I’m curious too now.

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I used to take magnesium but stopped as was unsure of taking with Clopidogrel, really miss this for sleeping and restless legs at night. I still take Vit D and B12. Never had to worry pre stroke as did not take prescribed medication. It would be nice to have a list of acceptable supplements.

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Magnesium helps the body produce melatonin which aids sleep but also the melatonin the body naturally produces is also an anticoagulant. These things might increase the efficacy of Clopidogrel but I don’t think they are a risk factor of a hemorrhagic stroke per se. Perhaps bruising or cuts may be more pronounced certainly.