My Mum has come off all her preventative meds apart from 75mg Asprin. She would come off this too but right now we (carers) give her the meds and so she can’t “refuse” it as such.
Pre-stroke she was put on B12 which she took for about a year but then decided to stop.
So before the stroke she was on no meds for a year or more. In her entire life she was only on B12 for about a year so. She was not comfortable with it but did it to “please” the “pushy” children who “knew better than her” - they were and are wrong!! Only she knows what’s good for her and that’s because she listens to her body.
We have discussed this topic and I believe Trace @Trace57 has some good information that might help you decide.
You have to choose what is right for you and my Mum’s advice has always been listen to your body..
It is likely you will get responses for and against coming off medication and so you will have to choose.